PRMT7 Polyclonal Antibody | G-AB-00622

PRMT7 Polyclonal Antibody | G-AB-00622 | Gentaur Antibodies

Overview: Protein arginine methyltransferase 7is aproteinthat in humans is encoded by thePRMT7gene.Argininemethylationis an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, usingS-adenosylmethionine (AdoMet) as the methyl donor. Arginine methylation is implicated inSignal Transduction, RNA transport, andRNA splicing. May be involved in etoposide-induced cytotoxicity, a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers. Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT) .

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: [Myelin basic protein]-arginine N-methyltransferase PRMT7, ANM7, FLJ10640, Histone-arginine N-methyltransferase PRMT7, KIAA1933, Myelin basic protein arginine N methyltransferase, OTTHUMP00000174863, PRMT7, Protein arginine methyltransferase 7, Protein arginine N-methyltransferase 7

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC000146

Clonality: Polyclonal

Immunogen: Recombinant protein of human PRMT7

Clone #:

Conjugation: Unconjugated

Swissprot: Q9NVM4

Santa Cruz: sc-48658/sc-48660/sc-48657/sc-98882

Calculated MW: 78 kDa

Observed MW:

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, ELISA

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PRMT7 Polyclonal Antibody DataSheet