PSMD1 Polyclonal Antibody | G-AB-09422

PSMD1 Polyclonal Antibody | G-AB-09422 | Gentaur Antibodies

Overview: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes the largest non-ATPase subunit of the 19S regulator lid, which is responsible for substrate recognition and binding. Alternatively spliced transcript variants have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: PSMD1, P112, Rpn2, S1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 5707

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human PSMD1 (NP_002798.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q99460

Santa Cruz:

Calculated MW: 102 kDa/105 kDa

Observed MW: 106 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PSMD1 Polyclonal Antibody DataSheet