PTCH1 Polyclonal Antibody | G-AB-00627
Gentaur Antibodies
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Gentaur Antibodies
PTCH1 Polyclonal Antibody | G-AB-00627
- SKU:
- G-AB-00627
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
PTCH1 Polyclonal Antibody | G-AB-00627 | Gentaur Antibodies
Overview: This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology, Neuroscience, Stem Cells
Synonyms: PTC, BCNS, HPE7, PTC1, PTCH, NBCCS, PTCH11
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: BC043542
Clonality: Polyclonal
Immunogen: Recombinant protein of human PTCH1
Clone #:
Conjugation: Unconjugated
Swissprot: Q13635
Santa Cruz: sc-6149/sc-6147/sc-9016
Calculated MW: 161 kDa
Observed MW:
Concentration: 0.5 mg/mL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: WB, IHC, ELISA
Dilution: WB 1:500-1:2000, IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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