PTCH1 Polyclonal Antibody | G-AB-08807

PTCH1 Polyclonal Antibody | G-AB-08807 | Gentaur Antibodies

Overview: This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Neuroscience, Stem Cells

Synonyms: PTCH1, BCNS, HPE7, NBCCS, PTC, PTC1, PTCH, PTCH11, patched 1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 5727

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human PTCH1 (NP_000255.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q13635

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PTCH1 Polyclonal Antibody DataSheet