PTCH1 Polyclonal Antibody | G-AB-00627

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$163.00 - $465.00
SKU:
G-AB-00627
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human, Mouse
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PTCH1 Polyclonal Antibody | G-AB-00627 | Gentaur Antibodies

Overview: This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Neuroscience, Stem Cells

Synonyms: PTC, BCNS, HPE7, PTC1, PTCH, NBCCS, PTCH11

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC043542

Clonality: Polyclonal

Immunogen: Recombinant protein of human PTCH1

Clone #:

Conjugation: Unconjugated

Swissprot: Q13635

Santa Cruz: sc-6149/sc-6147/sc-9016

Calculated MW: 161 kDa

Observed MW:

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PTCH1 Polyclonal Antibody DataSheet

Citation #1

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