PTPN18 Polyclonal Antibody | G-AB-12229

PTPN18 Polyclonal Antibody | G-AB-12229 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: PTPN18, BDP1, PTP-HSCF

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 26469

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human PTPN18 (NP_001135842.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q99952

Santa Cruz:

Calculated MW: 38 kDa/50 kDa

Observed MW: 60 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PTPN18 Polyclonal Antibody DataSheet