PTPN2 Polyclonal Antibody | G-AB-09745

PTPN2 Polyclonal Antibody | G-AB-09745 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction

Synonyms: PTPN2, PTN2, PTPT, TC-PTP, TCELLPTP, TCPTP

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 5771

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human PTPN2 (NP_536348.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P17706

Santa Cruz:

Calculated MW: 40 kDa/45 kDa/48 kDa

Observed MW: 45 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC, IF

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PTPN2 Polyclonal Antibody DataSheet