PTPN22 Polyclonal Antibody | G-AB-08553

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$156.96 - $334.80
SKU:
G-AB-08553
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
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PTPN22 Polyclonal Antibody | G-AB-08553 | Gentaur Antibodies

Overview: This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: PTPN22, LYP, LYP1, LYP2, PEP, PTPN22.5, PTPN22.6, PTPN8

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 26191

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human PTPN22 (NP_036543.4) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9Y2R2

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PTPN22 Polyclonal Antibody DataSheet