PTPRD Polyclonal Antibody | G-AB-12268
- 3 to 5 Working Days
- Human, Mouse
PTPRD Polyclonal Antibody | G-AB-12268 | Gentaur Antibodies
Overview: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5.
Category Type: Polyclonal Antibody
Research Areas: Neuroscience, Signal Transduction
Synonyms: PTPRD, HPTP, HPTPD, HPTPDELTA, PTPD, RPTPDELTA
Reactivity: Human, Mouse
Gene ID: 5789
Immunogen: Recombinant fusion protein of human PTPRD (NP_002830.1) .
Calculated MW: 156 kDa/169 kDa/212 kDa/214 kDa
Observed MW: 180-215 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.