PTPRN Polyclonal Antibody | G-AB-11071

PTPRN Polyclonal Antibody | G-AB-11071 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Neuroscience, Signal Transduction

Synonyms: PTPRN, IA-2, IA-2/PTP, IA2, ICA512, R-PTP-N

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 5798

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human PTPRN (NP_001186693.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q16849

Santa Cruz:

Calculated MW: 96 kDa/102 kDa/105 kDa

Observed MW: 66 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PTPRN Polyclonal Antibody DataSheet