RAD23B Polyclonal Antibody | G-AB-06376

RAD23B Polyclonal Antibody | G-AB-06376 | Gentaur Antibodies

Overview: The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER) . This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG) , which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: hHR 23b, hHR23B, HR 23B, HR23B, mHR 23B, mHR23B, p58, RAD 23B, RAD23 (S. cerevisiae) homolog B, RAD23 homolog B (S. cerevisiae) , RAD23 homolog B, RAD23 yeast homolog of B, Rad23b, RD23B, UV excision repair protein RAD23 homolog B, XP C repair complementing complex 58 kDa, XP C repair complementing complex 58 kDa protein, XP C repair complementing protein, XP-C repair-complementing complex 58 kDa protein, XPC repair complementing complex 58 kDa, XPC repair complementing complex 58 kDa protein, XPC repair complementing protein

Reactivity: Human, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC020973

Clonality: Polyclonal

Immunogen: Fusion protein of human RAD23B

Clone #:

Conjugation: Unconjugated

Swissprot: P54727

Santa Cruz:

Calculated MW: 43 kDa

Observed MW: Refer to figures

Concentration: 0.84 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

RAD23B Polyclonal Antibody DataSheet