RAE1 Polyclonal Antibody | G-AB-11268

RAE1 Polyclonal Antibody | G-AB-11268 | Gentaur Antibodies

Overview: Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly (A) -containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal Transduction, Tags & Cell Markers

Synonyms: RAE1, MIG14, MRNP41, Mnrp41, dJ481F12.3, dJ800J21.1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 8480

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human RAE1 (NP_003601.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P78406

Santa Cruz:

Calculated MW: 40 kDa

Observed MW: 40 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC, IF

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

RAE1 Polyclonal Antibody DataSheet