RAE1 Polyclonal Antibody | G-AB-11268
- 3 to 5 Working Days
- Human, Mouse, Rat
RAE1 Polyclonal Antibody | G-AB-11268 | Gentaur Antibodies
Overview: Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly (A) -containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal Transduction, Tags & Cell Markers
Synonyms: RAE1, MIG14, MRNP41, Mnrp41, dJ481F12.3, dJ800J21.1
Reactivity: Human, Mouse, Rat
Gene ID: 8480
Immunogen: Recombinant fusion protein of human RAE1 (NP_003601.1) .
Calculated MW: 40 kDa
Observed MW: 40 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IHC, IF
Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.