RAMP2 Polyclonal Antibody | G-AB-02842

RAMP2 Polyclonal Antibody | G-AB-02842 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs) . RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: Calcitonin receptor like receptor activity modifying protein 2, Calcitonin-receptor-like receptor activity-modifying protein 2, CRLR activity modifying protein 2, CRLR activity-modifying protein 2, OTTMUSP00000002615, OTTMUSP00000037624, RAMP2, RAMP2, Receptor (calcitonin) activity modifying protein 2, Receptor activity modifying protein 2, Receptor activity modifying protein 2 isoform, Receptor activity-modifying protein 2, RP23-281C18.6

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_005845

Clonality: Polyclonal

Immunogen: Synthetic peptide of human RAMP2

Clone #:

Conjugation: Unconjugated

Swissprot: O60895

Santa Cruz: sc-8852/sc-8853/sc-11380

Calculated MW: 20 kDa

Observed MW:

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, ELISA

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

RAMP2 Polyclonal Antibody DataSheet