RAP1A Polyclonal Antibody | G-AB-07267

RAP1A Polyclonal Antibody | G-AB-07267 | Gentaur Antibodies

Overview: This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs) , and inactivated by two groups of GTPase-activating proteins (GAPs) . The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: RAP1A, C21KG, G-22K, KREV-1, KREV1, RAP1, SMGP21

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 5906

Accession #:

Clonality:

Immunogen: A synthetic peptide of human RAP1A (NP_002875.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P62834

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

RAP1A Polyclonal Antibody DataSheet