RASSF1 Polyclonal Antibody | G-AB-07852
Gentaur Antibodies
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Gentaur Antibodies
RASSF1 Polyclonal Antibody | G-AB-07852
- SKU:
- G-AB-07852
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
RASSF1 Polyclonal Antibody | G-AB-07852 | Gentaur Antibodies
Overview: This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction
Synonyms: RASSF1, 123F2, NORE2A, RASSF1A, RDA32, REH3P21
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Gene ID: 11186
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human RASSF1 (NP_009113.3) .
Clone #:
Conjugation: Unconjugated
Swissprot: Q9NS23
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IHC, IF
Dilution: IHC 1:50-1:100 IF 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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