RFX6 Polyclonal Antibody | G-AB-06516

RFX6 Polyclonal Antibody | G-AB-06516 | Gentaur Antibodies

Overview: The nuclear protein encoded by this gene is a member of the regulatory factor X (RFX) family of transcription factors. Studies in mice suggest that this gene is specifically required for the differentiation of islet cells for the production of insulin, but not for the differentiation of pancreatic polypeptide-producing cells. It regulates the transcription factors involved in beta-cell maturation and function, thus, restricting the expression of the beta-cell differentiation and specification genes. Mutations in this gene are associated with Mitchell-Riley syndrome, which is characterized by neonatal diabetes with pancreatic hypoplasia, duodenal and jejunal atresia, and gall bladder agenesis.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling

Synonyms: DNA binding protein RFX6, Regulatory factor X domain containing protein 1, RFX6, RFX6 regulatory factor X, 6

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC039248

Clonality: Polyclonal

Immunogen: Fusion protein of human RFX6

Clone #:

Conjugation: Unconjugated

Swissprot: Q8HWS3

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 0.84 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

RFX6 Polyclonal Antibody DataSheet