RGR Polyclonal Antibody | G-AB-11949

RGR Polyclonal Antibody | G-AB-11949 | Gentaur Antibodies

Overview: This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively) . Alternative splicing results in multiple transcript variants encoding different isoforms.

Category Type: Polyclonal Antibody

Research Areas: Neuroscience, Signal Transduction

Synonyms: RGR, RP44

Reactivity: Rat

Host: Rabbit

Isotype: IgG

Gene ID: 5995

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human RGR (NP_002912.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P47804

Santa Cruz:

Calculated MW: 27 kDa/31 kDa/32 kDa

Observed MW: 32 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

RGR Polyclonal Antibody DataSheet