RGS4 Polyclonal Antibody | G-AB-09730

RGS4 Polyclonal Antibody | G-AB-09730 | Gentaur Antibodies

Overview: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Signal Transduction

Synonyms: RGS4, RGP4, SCZD9

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 5999

Accession #:

Clonality:

Immunogen: A synthetic peptide of human RGS4 (NP_005604.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P49798

Santa Cruz:

Calculated MW: 10 kDa/21 kDa/23 kDa/33 kDa

Observed MW: 30 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

RGS4 Polyclonal Antibody DataSheet