RIC8A Polyclonal Antibody | G-AB-06668

RIC8A Polyclonal Antibody | G-AB-06668 | Gentaur Antibodies

Overview: Guanine nucleotide exchange factor (GEF) , which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G (i) -alpha protein, possibly leading to release G (i) -alpha-GTP and NuMA proteins from the NuMA-GPSM2-G (i) -alpha-GDP complex (By similarity) . Also acts as an activator for G (q) -alpha (GNAQ) protein by enhancing the G (q) -coupled receptor-mediated ERK activation.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction

Synonyms: MGC104517, MGC131931, MGC148073, MGC148074, Protein Ric-8A, resistance to inhibitors of cholinesterase 8 homolog A (C. elegans) , RIC8, RIC8A, RIC8A, Synembryn-A

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC011821

Clonality: Polyclonal

Immunogen: Fusion protein of human RIC8A

Clone #:

Conjugation: Unconjugated

Swissprot: Q9NPQ8

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1.44 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

RIC8A Polyclonal Antibody DataSheet