RNF7 Polyclonal Antibody | G-AB-11615

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$218.00 - $465.00
SKU:
G-AB-11615
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human
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RNF7 Polyclonal Antibody | G-AB-11615 | Gentaur Antibodies

Overview: The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and Signal Transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII) . The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1 (CDKN1B) . Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism

Synonyms: RNF7, CKBBP1, ROC2, SAG

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 9616

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human RNF7 (NP_055060.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9UBF6

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:20-1:50

Storage: Store at -20°C. Avoid freeze / thaw cycles.

RNF7 Polyclonal Antibody DataSheet