RPS3 Polyclonal Antibody | G-AB-08316

RPS3 Polyclonal Antibody | G-AB-08316 | Gentaur Antibodies

Overview: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit, where it forms part of the domain where translation is initiated. The protein belongs to the S3P family of ribosomal proteins. Studies of the mouse and rat proteins have demonstrated that the protein has an extraribosomal role as an endonuclease involved in the repair of UV-induced DNA damage. The protein appears to be located in both the cytoplasm and nucleus but not in the nucleolus. Higher levels of expression of this gene in colon adenocarcinomas and adenomatous polyps compared to adjacent normal colonic mucosa have been observed. This gene is co-transcribed with the small nucleolar RNA genes U15A and U15B, which are located in its first and fifth introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell biology, Epigenetics and Nuclear Signaling

Synonyms: RPS3, S3

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 6188

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human RPS3 (NP_000996.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P23396

Santa Cruz:

Calculated MW: 26 kDa/28 kDa

Observed MW: 27 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

RPS3 Polyclonal Antibody DataSheet