RTN3 Polyclonal Antibody | G-AB-08952

RTN3 Polyclonal Antibody | G-AB-08952 | Gentaur Antibodies

Overview: This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1) , and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: RTN3, ASYIP, HAP, NSPL2, NSPLII, RTN3-A1

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 10313

Accession #:

Clonality:

Immunogen: A synthetic peptide of human RTN3 (NP_006045.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: O95197

Santa Cruz:

Calculated MW: 23 kDa/25 kDa/26 kDa/27 kDa/100 kDa/110 kDa/112 kDa

Observed MW: 26 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

RTN3 Polyclonal Antibody DataSheet