RUNX2 Polyclonal Antibody | G-AB-00222

RUNX2 Polyclonal Antibody | G-AB-00222 | Gentaur Antibodies

Overview: This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD) . Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Developmental Biology, Stem Cells

Synonyms: Acute myeloid leukemia 3 protein, Alpha subunit 1, AML3, CBF alpha 1, CBF-alpha-1, CBFA1, CCD, CCD1, Cleidocranial dysplasia 1, Core binding factor, Core binding factor runt domain alpha subunit 1, Core binding factor subunit alpha 1, Core-binding factor subunit alpha-1, MGC120022, MGC120023, Oncogene AML 3, Oncogene AML-3, OSF 2, OSF-2, OSF2, Osteoblast specific transcription factor 2, Osteoblast-specific transcription factor 2, OTTHUMP00000016533, PEA2 alpha A, PEA2-alpha A, PEA2aA, PEBP2 alpha A, PEBP2-alpha A, PEBP2A1, PEBP2A2, PEBP2aA, PEBP2aA1, Polyomavirus enhancer binding protein 2 alpha A subunit, Polyomavirus enhancer-binding protein 2 alpha A subunit, Runt domain, Runt related transcription factor 2, Runt-related transcription factor 2, RUNX2, RUNX2, SL3 3 enhancer factor 1 alpha A subunit, SL3-3 enhancer factor 1 alpha A subunit, SL3/AKV core binding factor alpha A subunit, SL3/AKV core-binding factor alpha A subunit

Reactivity: Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #:

Clonality: Polyclonal

Immunogen: Recombinant Rat Runt-related transcription factor 2 protein

Clone #:

Conjugation: Unconjugated

Swissprot: Q9Z2J9

Santa Cruz:

Calculated MW: 24 kDa

Observed MW: 24 kDa

Concentration: 0.65 mg/mL

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Purification method: Antigen Affinity Purification

Application: WB

Dilution: WB 1:500-1:1000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

RUNX2 Polyclonal Antibody DataSheet