S100A4 Polyclonal Antibody | G-AB-12676
- 3 to 5 Working Days
- Human, Rat
S100A4 Polyclonal Antibody | G-AB-12676 | Gentaur Antibodies
Overview: S100A4 is a member of the S100 family of calcium-binding proteins. The S100 family members have been involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A4 is known to localize to and function in the nucleus, cytoplasm of cells and the extracellular space. S100A4 has also been shown to be associated with tumor growth, motility, invasion, metastasis, angiogenesis, apoptosis and chemoresistance. It is a fibroblast-specific protein associated with mesenchymal cell morphology and motility, is expressed during epithelial-mesenchymal transformations (EMT) in vivo. It is an improved marker for lung fibroblasts that could be useful for investigating the pathogenesis of pulmonary fibrosis. Overexpression of S100A4 is correlated with a worse prognosis inpatients with various types of cancer.
Category Type: Polyclonal Antibody
Research Areas: Cardiovascular, Signal Transduction, Cancer
Synonyms: 18A2, 42A, calcium Placental protein, Calvasculin, CAPL, Fibroblast specific protein 1, FSP1, Leukemia multidrug resistance associated protein, Malignant transformation suppression 1, Metastasin, MTS1, OTTHUMP00000015467, OTTHUMP00000015468, P9KA, PEL98, Placental calcium-binding protein, Protein Mts1, Protein S100 A4, S100 calcium binding protein A4, S100a4
Reactivity: Human, Rat
Gene ID: 6275
Immunogen: Recombinant Human Protein S100-A4 protein
Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Purification method: Antigen Affinity Purification
Dilution: IHC 1:100-1:400
Storage: Store at -20℃. Avoid freeze / thaw cycles.