SAG Polyclonal Antibody | G-AB-08023

SAG Polyclonal Antibody | G-AB-08023 | Gentaur Antibodies

Overview: Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: SAG, RP47, S-AG

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 6295

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human SAG (NP_000532.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P10523

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SAG Polyclonal Antibody DataSheet