SCN11A Polyclonal Antibody | G-AB-01486

SCN11A Polyclonal Antibody | G-AB-01486 | Gentaur Antibodies

Overview: Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.

Category Type: Polyclonal Antibody

Research Areas: Neuroscience

Synonyms: hNaN, NaN, NAV1.9, Peripheral nerve sodium channel 5, PN 5, PN5, SCN 11A, SCN 12A, Scn11a, SCN12A, SCNBA, Sensory neuron sodium channel 2, SNS 2, SNS2, Sodium channel protein type 11 subunit alpha, Sodium channel protein type XI subunit alpha, Sodium channel voltage gated type XI alpha, Sodium channel voltage gated type XI alpha polypeptide, Sodium channel voltage gated type XI alpha subunit, Sodium channel voltage gated type XII alpha polypeptide, Voltage gated sodium channel Nav1.9, Voltage gated sodium channel subunit alpha Nav1.9, Voltage-gated sodium channel subunit alpha Nav1.9

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_054858.2

Clonality: Polyclonal

Immunogen: Synthetic peptide of human SCN11A

Clone #:

Conjugation: Unconjugated

Swissprot: Q9UI33

Santa Cruz: sc-103058/sc-103060

Calculated MW:

Observed MW:

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SCN11A Polyclonal Antibody DataSheet