SDHB Polyclonal Antibody | G-AB-12699

SDHB Polyclonal Antibody | G-AB-12699 | Gentaur Antibodies

Overview: Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Metabolism, Signal Transduction

Synonyms: CWS2, DHSB, Ip, Iron sulfur subunit, Iron sulfur subunit of complex II, Iron-sulfur subunit of complex II, mitochondrial, PGL 4, PGL4, SDH 1, SDH, SDH1, SDH2, SDH2, homolog of, SdhB, SDHIP, Succinate dehydrogenase [ubiquinone] iron sulfur protein mitochondrial, Succinate dehydrogenase [ubiquinone] iron sulfur subunit, Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial, Succinate Dehydrogenase 1 Iron Sulfur Subunit, Succinate Dehydrogenase 2, S. cerevisiae, homolog of, Succinate dehydrogenase complex iron sulfur subunit B, Succinate dehydrogenase complex subunit B iron sulfur, Succinate Dehydrogenase Complex Subunit B Iron Sulfur Protein, succinate dehydrogenase complex, subunit B, iron sulfur (Ip) , Succinate dehydrogenase iron sulfur protein

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 6390

Accession #:

Clonality: Polyclonal

Immunogen: Recombinant Human Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial protein

Clone #:

Conjugation:

Swissprot: P21912

Santa Cruz:

Calculated MW: 31 kDa

Observed MW: 31 kDa

Concentration: 1mg/mL

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.

Purification method: Antigen Affinity Purification

Application: WB, IHC

Dilution: WB 1:20000-1:100000 IHC 1:100-1:400

Storage: Store at -20℃. Avoid freeze / thaw cycles.

SDHB Polyclonal Antibody DataSheet