SDHB Polyclonal Antibody | G-AB-07447
- 3 to 5 Working Days
- Human, Mouse, Rat
SDHB Polyclonal Antibody | G-AB-07447 | Gentaur Antibodies
Overview: Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell biology, Metabolism, Signal Transduction
Synonyms: SDHB, CWS2, IP, PGL4, SDH, SDH1, SDH2, SDHIP
Reactivity: Human, Mouse, Rat
Gene ID: 6390
Immunogen: Recombinant fusion protein of human SDHB (NP_002991.2) .
Calculated MW: 31 kDa
Observed MW: 32 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IHC
Dilution: WB 1:500-1:2000 IHC 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.