SDHB Polyclonal Antibody | G-AB-12699
- 3 to 5 Working Days
- Human, Mouse, Rat
SDHB Polyclonal Antibody | G-AB-12699 | Gentaur Antibodies
Overview: Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology, Metabolism, Signal Transduction
Synonyms: CWS2, DHSB, Ip, Iron sulfur subunit, Iron sulfur subunit of complex II, Iron-sulfur subunit of complex II, mitochondrial, PGL 4, PGL4, SDH 1, SDH, SDH1, SDH2, SDH2, homolog of, SdhB, SDHIP, Succinate dehydrogenase [ubiquinone] iron sulfur protein mitochondrial, Succinate dehydrogenase [ubiquinone] iron sulfur subunit, Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial, Succinate Dehydrogenase 1 Iron Sulfur Subunit, Succinate Dehydrogenase 2, S. cerevisiae, homolog of, Succinate dehydrogenase complex iron sulfur subunit B, Succinate dehydrogenase complex subunit B iron sulfur, Succinate Dehydrogenase Complex Subunit B Iron Sulfur Protein, succinate dehydrogenase complex, subunit B, iron sulfur (Ip) , Succinate dehydrogenase iron sulfur protein
Reactivity: Human, Mouse, Rat
Gene ID: 6390
Immunogen: Recombinant Human Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial protein
Calculated MW: 31 kDa
Observed MW: 31 kDa
Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Purification method: Antigen Affinity Purification
Application: WB, IHC
Dilution: WB 1:20000-1:100000 IHC 1:100-1:400
Storage: Store at -20℃. Avoid freeze / thaw cycles.