SELPLG Polyclonal Antibody | G-AB-02111

SELPLG Polyclonal Antibody | G-AB-02111 | Gentaur Antibodies

Overview: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Immunology

Synonyms: CD 162, CD162, CD162 antigen, CLA, Cutaneous lymphocyte associated associated antigen, P selectin glycoprotein ligand 1, P selectin glycoprotein ligand 1 precursor, P-selectin glycoprotein ligand 1, PSGL 1, PSGL-1, PSGL1, Selectin P ligand, SELPL, SELPLG

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC029782

Clonality: Polyclonal

Immunogen: Recombinant protein of human SELPLG

Clone #:

Conjugation: Unconjugated

Swissprot: Q14242

Santa Cruz: sc-10169/sc-10172/sc-20929

Calculated MW:

Observed MW:

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SELPLG Polyclonal Antibody DataSheet