SEMA4A Polyclonal Antibody | G-AB-02667

SEMA4A Polyclonal Antibody | G-AB-02667 | Gentaur Antibodies

Overview: This gene encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF) -mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10) . Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Neuroscience

Synonyms: CORD10, RP11 54H19 2, RP35, SEM4A, Sema B, Sema domain immunoglobulin domain Ig transmembrane domain TM and short cytoplasmic domain 4A, Sema domain immunoglobulin domain Ig transmembrane domain TM and short cytoplasmic domain semaphorin 4A, Sema domain, immunoglobulin domain (Ig) , transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) , Sema4a, SEMAB, Semaphorin 4A precursor, Semaphorin B, Semaphorin-4A, Semaphorin-B, SEMB

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC020974

Clonality: Polyclonal

Immunogen: Recombinant protein of human SEMA4A

Clone #:

Conjugation: Unconjugated

Swissprot: Q9H3S1

Santa Cruz: sc-46258/sc-46255/sc-67073

Calculated MW:

Observed MW:

Concentration: 0.8 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:30-1:150

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SEMA4A Polyclonal Antibody DataSheet