SETD2 Polyclonal Antibody | G-AB-10302

SETD2 Polyclonal Antibody | G-AB-10302 | Gentaur Antibodies

Overview: Huntington's disease (HD) , a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: SETD2, HBP231, HIF-1, HIP-1, HSPC069, HYPB, KMT3A, LLS, SET2, p231HBP

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 29072

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human SETD2 (NP_054878.5) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9BYW2

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SETD2 Polyclonal Antibody DataSheet