SF3B1 Polyclonal Antibody | G-AB-09200

SF3B1 Polyclonal Antibody | G-AB-09200 | Gentaur Antibodies

Overview: This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP) . The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: SF3B1, Hsh155, MDS, PRP10, PRPF10, SAP155, SF3b155

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 23451

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human SF3B1 (NP_001005526.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: O75533

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SF3B1 Polyclonal Antibody DataSheet