SF3B2 Polyclonal Antibody | G-AB-10876

SF3B2 Polyclonal Antibody | G-AB-10876 | Gentaur Antibodies

Overview: This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP) . The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: SF3B2, Cus1, SAP145, SF3B145, SF3b1, SF3b150

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 10992

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human SF3B2 (NP_006833.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q13435

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SF3B2 Polyclonal Antibody DataSheet