Signal Transduction Antibody

ECSIT Polyclonal Antibody | G-AB-06675 | Gentaur AntibodiesOverview: Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1...

SCCPDH Polyclonal Antibody | G-AB-06673 | Gentaur AntibodiesOverview: SCCPDH (Probable saccharopine dehydrogenase) is a 429 amino acid protein that belongs to the saccharopine dehydrogenase family...

RIC8A Polyclonal Antibody | G-AB-06668 | Gentaur AntibodiesOverview: Guanine nucleotide exchange factor (GEF) , which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1...

UXS1 Polyclonal Antibody | G-AB-06667 | Gentaur AntibodiesOverview: This gene encodes an enzyme found in the perinuclear Golgi which catalyzes the synthesis of UDP-xylose used in glycosaminoglycan...

FDPS Polyclonal Antibody | G-AB-06666 | Gentaur AntibodiesOverview: This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl...

PHKG2 Polyclonal Antibody | G-AB-06663 | Gentaur AntibodiesOverview: Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the...

LIPA Polyclonal Antibody | G-AB-06660 | Gentaur AntibodiesOverview: This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase) . This enzyme functions in the...

PDHA1 Polyclonal Antibody | G-AB-06656 | Gentaur AntibodiesOverview: PDHA1 (Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial) is also named as PHE1A.It is one of the 3...

PCYT2 Polyclonal Antibody | G-AB-06655 | Gentaur AntibodiesOverview: This gene encodes an enzyme that catalyzes the formation of CDP-ethanolamine from CTP and phosphoethanolamine in the Kennedy...

ATP6V1C1 Polyclonal Antibody | G-AB-06653 | Gentaur AntibodiesOverview: This gene encodes a component of vacuolar ATPase (V-ATPase) , a multisubunit enzyme that mediates acidification of...

RAB3IL1 Polyclonal Antibody | G-AB-06652 | Gentaur AntibodiesOverview: This gene encodes a guanine nucleotide exchange factor for the ras-related protein Rab3A. The encoded protein binds Rab3a and...

LDHAL6B Polyclonal Antibody | G-AB-06650 | Gentaur AntibodiesOverview: LDHAL6B belongs to the LDH/MDH superfamily. LDH family. The specific function of the protein remains unknown.Category Type:...

MECR Polyclonal Antibody | G-AB-06645 | Gentaur AntibodiesOverview: The protein encoded by this gene is an oxidoreductase that catalyzes the last step in mitochondrial fatty acid synthesis. Defects...

RABEPK Polyclonal Antibody | G-AB-06643 | Gentaur AntibodiesOverview: Rab9 effector required for endosome to trans-Golgi network (TGN) transport.Category Type: Polyclonal AntibodyResearch Areas: Cell...

GMDS Polyclonal Antibody | G-AB-06642 | Gentaur AntibodiesOverview: GDP-mannose 4, 6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first...

LMCD1 Polyclonal Antibody | G-AB-06638 | Gentaur AntibodiesOverview: This gene encodes a member of the LIM-domain family of zinc finger proteins. The encoded protein contains an N-terminal...

GMPPB Polyclonal Antibody | G-AB-06636 | Gentaur AntibodiesOverview: This gene is thought to encode a GDP-mannose pyrophosphorylase. The encoded protein catalyzes the conversion of...

GPD1L Polyclonal Antibody | G-AB-06631 | Gentaur AntibodiesOverview: The protein encoded by this gene catalyzes the conversion of sn-glycerol 3-phosphate to glycerone phosphate. The encoded protein...

LRG1 Polyclonal Antibody | G-AB-06629 | Gentaur AntibodiesOverview: The leucine-rich repeat (LRR) family of proteins, including LRG1, have been shown to be involved in protein-protein interaction,...

HMGCLL1 Polyclonal Antibody | G-AB-06626 | Gentaur AntibodiesOverview: Non-mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)...

GIMAP2 Polyclonal Antibody | G-AB-06625 | Gentaur AntibodiesOverview: This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of...

PTH1R Polyclonal Antibody | G-AB-06620 | Gentaur AntibodiesOverview: The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for...

KCTD13 Polyclonal Antibody | G-AB-06618 | Gentaur AntibodiesOverview: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton...

ECH1 Polyclonal Antibody | G-AB-06616 | Gentaur AntibodiesOverview: This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to...

PRKAG2 Polyclonal Antibody | G-AB-06615 | Gentaur AntibodiesOverview: AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta...

TRAPPC1 Polyclonal Antibody | G-AB-06611 | Gentaur AntibodiesOverview: This gene product plays a role in vesicular transport of proteins to the Golgi apparatus from the endoplasmic reticulum. The...

PPP1R3C Polyclonal Antibody | G-AB-06610 | Gentaur AntibodiesOverview: This gene encodes a carbohydrate binding protein that is a subunit of the protein phosphatase 1 (PP1) complex. PP1 catalyzes...

ATP5PD Polyclonal Antibody | G-AB-06607 | Gentaur AntibodiesOverview: Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane...

NKD2 Polyclonal Antibody | G-AB-06606 | Gentaur AntibodiesOverview: This gene encodes a member of a family of proteins that function as negative regulators of Wnt receptor signaling through...

NAPRT Polyclonal Antibody | G-AB-06604 | Gentaur AntibodiesOverview: Nicotinic acid (NA) is a coenzyme in cellular redox reactions, and is an essential component of metabolic pathways in all living...

HCCS Polyclonal Antibody | G-AB-06594 | Gentaur AntibodiesOverview: The protein encoded by this gene is an enzyme that covalently links a heme group to the apoprotein of cytochrome c. Defects in this...

SULT4A1 Polyclonal Antibody | G-AB-06593 | Gentaur AntibodiesOverview: SULT4A1, also named as SULTX3, NST, ST4A1, hBR-STL and hBR-STL-1, belongs to the sulfotransferase 1 family. It may catalyze the...

THTPA Polyclonal Antibody | G-AB-06590 | Gentaur AntibodiesOverview: This gene encodes an enzyme which catalyzes the biosynthesis of thiamine disphophate (vitamin B1) by hydrolysis of thiamine...

PAFAH1B2 Polyclonal Antibody | G-AB-06589 | Gentaur AntibodiesOverview: Platelet-activating factor acetylhydrolase (PAFAH) inactivates platelet-activating factor (PAF) into acetate and LYSO-PAF. This...

GSTK1 Polyclonal Antibody | G-AB-06586 | Gentaur AntibodiesOverview: This gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular...

THNSL1 Polyclonal Antibody | G-AB-06584 | Gentaur AntibodiesOverview: THNSL1 (threonine synthase-like 1) , also known as TSH1, is a 743 amino acid member of the serine/threonine dehydratase family...

MOB1A Polyclonal Antibody | G-AB-06580 | Gentaur AntibodiesOverview: MOB1 was first identified in yeast as a protein that binds to Mps with essential roles in the completion of mitosis and the...

SEC22B Polyclonal Antibody | G-AB-06579 | Gentaur AntibodiesOverview: The protein encoded by this gene is a member of the SEC22 family of vesicle trafficking proteins. It seems to complex with SNARE...

HS1BP3 Polyclonal Antibody | G-AB-06578 | Gentaur AntibodiesOverview: The protein encoded by this gene shares similarity with mouse Hs1bp3, an Hcls1/Hs1-interacting protein that may be involved in...

MTHFS Polyclonal Antibody | G-AB-06575 | Gentaur AntibodiesOverview: The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,...

ARL4D Polyclonal Antibody | G-AB-06574 | Gentaur AntibodiesOverview: ADP-ribosylation factor 4D is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4D is closely similar to...

PPM1B Polyclonal Antibody | G-AB-06569 | Gentaur AntibodiesOverview: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to...

FUNDC2 Polyclonal Antibody | G-AB-06567 | Gentaur AntibodiesOverview: FUNDC2 (FUN14 domain-containing protein 2) , also known as HCC-3 (cervical cancer proto-oncogene 3 protein) , HCBP6 (hepatitis C...

DHFR Polyclonal Antibody | G-AB-06566 | Gentaur AntibodiesOverview: Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of...

IFT27 Polyclonal Antibody | G-AB-06565 | Gentaur AntibodiesOverview: This gene encodes a GTP-binding protein that is a core component of the intraflagellar transport complex B. Characterization of...

IFT22 Polyclonal Antibody | G-AB-06562 | Gentaur AntibodiesOverview: Small GTPase-like component of the intraflagellar transport (IFT) complex B.Category Type: Polyclonal AntibodyResearch Areas:...

PDAP1 Polyclonal Antibody | G-AB-06559 | Gentaur AntibodiesOverview: The protein encoded by this gene is a phosphoprotein that may upregulate the PDGFA-stimulated growth of fibroblasts and also...

FMNL2 Polyclonal Antibody | G-AB-06557 | Gentaur AntibodiesOverview: This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell...

MPV17 Polyclonal Antibody | G-AB-06555 | Gentaur AntibodiesOverview: This gene encodes a mitochondrial inner membrane protein that is implicated in the metabolism of reactive oxygen species...

TXNDC12 Polyclonal Antibody | G-AB-06553 | Gentaur AntibodiesOverview: This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif...

ZNF580 Polyclonal Antibody | G-AB-06552 | Gentaur AntibodiesOverview: Involved in the regulation of endothelial cell proliferation and migration. Mediates H2O2-induced leukocyte chemotaxis by...

ARL2BP Polyclonal Antibody | G-AB-06549 | Gentaur AntibodiesOverview: ADP-ribosylation factor (ARF) -like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related...

ILF3 Polyclonal Antibody | G-AB-06548 | Gentaur AntibodiesOverview: This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs,...

ARPC5L Polyclonal Antibody | G-AB-06544 | Gentaur AntibodiesOverview: May function as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an...

NPC2 Polyclonal Antibody | G-AB-06543 | Gentaur AntibodiesOverview: This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of...

PSD4 Polyclonal Antibody | G-AB-06526 | Gentaur AntibodiesOverview: Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class...

IPO11 Polyclonal Antibody | G-AB-06523 | Gentaur AntibodiesOverview: Importins, including IPO11, are a members of the karyopherin/importin-beta family of transport receptors (see KPNB1; 602738) that...

NID2 Polyclonal Antibody | G-AB-06522 | Gentaur AntibodiesOverview: This gene encodes a member of the nidogen family of basement membrane proteins. This protein is a cell-adhesion protein that binds...

TCOF1 Polyclonal Antibody | G-AB-06520 | Gentaur AntibodiesOverview: This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription...

SLC26A3 Polyclonal Antibody | G-AB-06510 | Gentaur AntibodiesOverview: The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in...

MCCC1 Polyclonal Antibody | G-AB-06508 | Gentaur AntibodiesOverview: This gene encodes the large subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the...

NGEF Polyclonal Antibody | G-AB-06507 | Gentaur AntibodiesOverview: Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in...

CALCOCO1 Polyclonal Antibody | G-AB-06506 | Gentaur AntibodiesOverview: CALCOCO1 (calcium-binding and coiled-coil domain-containing protein 1) , also known as cocoa, calphoglin, sarcoma antigen...

PDIA4 Polyclonal Antibody | G-AB-06502 | Gentaur AntibodiesOverview: PDIA4 (Protein disulfide-isomerase A4) is also named as ERP70, ERP72 and belongs to the protein disulfide isomerase family. It...

EIF2AK1 Polyclonal Antibody | G-AB-06501 | Gentaur AntibodiesOverview: The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to...

NUP58 Polyclonal Antibody | G-AB-06500 | Gentaur AntibodiesOverview: This gene encodes a member of the nucleoporin family that shares 87% sequence identity with rat nucleoporin p58. The protein is...

PPM1G Polyclonal Antibody | G-AB-06495 | Gentaur AntibodiesOverview: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to...

ABLIM3 Polyclonal Antibody | G-AB-06494 | Gentaur AntibodiesOverview: This gene encodes a member of the actin-binding LIM (abLIM) family of proteins. These proteins are characterized by an N-terminal...

DNPEP Polyclonal Antibody | G-AB-06490 | Gentaur AntibodiesOverview: The protein encoded by this gene is an aminopeptidase which prefers acidic amino acids, and specifically favors aspartic acid over...

FNTB Polyclonal Antibody | G-AB-06487 | Gentaur AntibodiesOverview: Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a...

ERAL1 Polyclonal Antibody | G-AB-06486 | Gentaur AntibodiesOverview: The protein encoded by this gene is a GTPase that localizes to the mitochondrion. The encoded protein binds to the 3' terminal...

ENO3 Polyclonal Antibody | G-AB-06484 | Gentaur AntibodiesOverview: This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme is found in skeletal muscle cells in the...

GPSM1 Polyclonal Antibody | G-AB-06483 | Gentaur AntibodiesOverview: G-protein signaling modulators (GPSMs) play diverse functional roles through their interaction with G-protein subunits. This gene...

TTLL1 Polyclonal Antibody | G-AB-06481 | Gentaur AntibodiesOverview: Catalytic subunit of the neuronal tubulin polyglutamylase complex. Modifies alpha- and beta-tubulin, generating side chains of...

GCAT Polyclonal Antibody | G-AB-06480 | Gentaur AntibodiesOverview: The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine...

ADRM1 Polyclonal Antibody | G-AB-06477 | Gentaur AntibodiesOverview: The 26S proteasome is a key component of the ubiquitin-proteasome system, a process responsible for the majority of cellular...

FLOT2 Polyclonal Antibody | G-AB-06474 | Gentaur AntibodiesOverview: Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and Signal Transduction. This gene encodes...

GKAP1 Polyclonal Antibody | G-AB-06470 | Gentaur AntibodiesOverview: This gene encodes a protein that is highly similar to the mouse cGMP-dependent protein kinase anchoring protein 42kDa. The mouse...

COPE Polyclonal Antibody | G-AB-06469 | Gentaur AntibodiesOverview: The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to...

TPMT Polyclonal Antibody | G-AB-06454 | Gentaur AntibodiesOverview: This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and...

QDPR Polyclonal Antibody | G-AB-06453 | Gentaur AntibodiesOverview: This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin...

RAC3 Polyclonal Antibody | G-AB-06447 | Gentaur AntibodiesOverview: The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this...

TIPRL Polyclonal Antibody | G-AB-06442 | Gentaur AntibodiesOverview: TIPRL is an inhibitory regulator of protein phosphatase-2A (PP2A) (see PPP2CA; MIM 176915) , PP4 (see PPP4C; MIM 602035) , and PP6...

ISCU Polyclonal Antibody | G-AB-06440 | Gentaur AntibodiesOverview: This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the...

GLYAT Polyclonal Antibody | G-AB-06438 | Gentaur AntibodiesOverview: The glycine-N-acyltransferase protein conjugates glycine with acyl-CoA substrates in the mitochondria. The protein is thought to...

MTAP Polyclonal Antibody | G-AB-06434 | Gentaur AntibodiesOverview: This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and...

THAP12 Polyclonal Antibody | G-AB-06432 | Gentaur AntibodiesOverview: Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR) . May block the PKR-inhibitory function of...

PDRG1 Polyclonal Antibody | G-AB-06429 | Gentaur AntibodiesOverview: PDRG1 (P53 And DNA Damage Regulated 1) is a Protein Coding gene. GO annotations related to this gene include unfolded protein...

AP1S1 Polyclonal Antibody | G-AB-06428 | Gentaur AntibodiesOverview: The protein encoded by this gene is part of the clathrin coat assembly complex which links clathrin to receptors in coated...

SPIRE1 Polyclonal Antibody | G-AB-06425 | Gentaur AntibodiesOverview: Spire proteins, such as SPIRE1, are highly conserved between species. They belong to the family of Wiskott-Aldrich homology...

UQCC2 Polyclonal Antibody | G-AB-06424 | Gentaur AntibodiesOverview: This gene encodes a nucleoid protein localized to the mitochondria inner membrane. The encoded protein affects regulation of...

SAA1 Polyclonal Antibody | G-AB-06421 | Gentaur AntibodiesOverview: This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed...

C8orf4 Polyclonal Antibody | G-AB-06419 | Gentaur AntibodiesOverview: This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the...

ATP5L Polyclonal Antibody | G-AB-06417 | Gentaur AntibodiesOverview: Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane...

MGP Polyclonal Antibody | G-AB-06416 | Gentaur AntibodiesOverview: Matrix Gla protein (MGP) is is a vitamin K-dependent, extracellular matrix protein. MGP plays a pivotal role in preventing soft...

PLGLB2 Polyclonal Antibody | G-AB-06415 | Gentaur AntibodiesOverview: Cleavage of the serine proteinase plasminogen to form plasmin is the central event in the dissolution of blood clots by the...

EPM2A Polyclonal Antibody | G-AB-06413 | Gentaur AntibodiesOverview: This gene encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the...

TIMM8A Polyclonal Antibody | G-AB-06412 | Gentaur AntibodiesOverview: This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the...

GBA2 Polyclonal Antibody | G-AB-06411 | Gentaur AntibodiesOverview: This gene encodes a microsomal beta-glucosidase that catalyzes the hydrolysis of bile acid 3-O-glucosides as endogenous compounds...

GPRASP2 Polyclonal Antibody | G-AB-06409 | Gentaur AntibodiesOverview: The protein encoded by this gene is a member of a family that regulates the activity of G protein-coupled receptors (GPCRs) ...