SKAP2 Polyclonal Antibody | G-AB-09173

SKAP2 Polyclonal Antibody | G-AB-09173 | Gentaur Antibodies

Overview: The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: SKAP2, PRAP, RA70, SAPS, SCAP2, SKAP-HOM, SKAP55R

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 8935

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human SKAP2 (NP_003921.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: O75563

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SKAP2 Polyclonal Antibody DataSheet