SLC22A5 Polyclonal Antibody | G-AB-08814

SLC22A5 Polyclonal Antibody | G-AB-08814 | Gentaur Antibodies

Overview: Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP) , an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy. Alternative splicing of this gene results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Metabolism, Signal Transduction

Synonyms: SLC22A5, CDSP, OCTN2

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 6584

Accession #:

Clonality:

Immunogen: Recombinant protein of human SLC22A5

Clone #:

Conjugation: Unconjugated

Swissprot: O76082

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SLC22A5 Polyclonal Antibody DataSheet