SLC7A11 Polyclonal Antibody | G-AB-03533

SLC7A11 Polyclonal Antibody | G-AB-03533 | Gentaur Antibodies

Overview: This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc (-) , the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell biology, Metabolism, Signal Transduction

Synonyms: Amino acid transport system xc xCT, Amino acid transport system xc-, Calcium channel blocker resistance protein CCBR1, Calcium channel blocker resistance protein CCBR1, CCBR1, Cysteine/glutamate transporter, Cystine/glutamate transporter, OTTHUMP00000164578, SLC7A11, Solute carrier family 7 (anionic amino acid transporter light chain, xc- system) , member 11, solute carrier family 7, Solute carrier family 7 member 11, Solute carrier family 7, (cationic amino acid transporter, y+ system) member 11, SYSTEM Xc (-) TRANSPORTER-RELATED PROTEIN, xCT, XCT

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_055146

Clonality: Polyclonal

Immunogen: Synthetic peptide of human SLC7A11

Clone #:

Conjugation: Unconjugated

Swissprot: Q9UPY5

Santa Cruz: sc-79359/sc-79360/sc-98552

Calculated MW: 55 kDa

Observed MW:

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:20-100, ELISA 1:2000-5000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SLC7A11 Polyclonal Antibody DataSheet