SMAD7 Polyclonal Antibody | G-AB-07764

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$156.96 - $334.80
SKU:
G-AB-07764
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
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SMAD7 Polyclonal Antibody | G-AB-07764 | Gentaur Antibodies

Overview: The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1) , leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3) . Several transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms: SMAD7, CRCS3, MADH7, MADH8

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 4092

Accession #:

Clonality:

Immunogen: A synthetic peptide of human SMAD7 (NP_005895.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: O15105

Santa Cruz:

Calculated MW: 23 kDa/46 kDa

Observed MW: 46 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SMAD7 Polyclonal Antibody DataSheet

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