SNX15 Polyclonal Antibody | G-AB-12340

SNX15 Polyclonal Antibody | G-AB-12340 | Gentaur Antibodies

Overview: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: SNX15, HSAF001435

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 29907

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human SNX15 (NP_037438.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9NRS6

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SNX15 Polyclonal Antibody DataSheet