SOCS3 Polyclonal Antibody | G-AB-07234

SOCS3 Polyclonal Antibody | G-AB-07234 | Gentaur Antibodies

Overview: This gene encodes a member of the STAT-induced STAT inhibitor (SSI) , also known as suppressor of cytokine signaling (SOCS) , family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN) -gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Immunology, Signal Transduction, Stem Cells

Synonyms: SOCS3, ATOD4, CIS3, Cish3, SOCS-3, SSI-3, SSI3

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 9021

Accession #:

Clonality:

Immunogen: A synthetic peptide of human SOCS3 (NP_003946.3) .

Clone #:

Conjugation: Unconjugated

Swissprot: O14543

Santa Cruz:

Calculated MW: 24 kDa

Observed MW: 33 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SOCS3 Polyclonal Antibody DataSheet