SORD Polyclonal Antibody | G-AB-06894

SORD Polyclonal Antibody | G-AB-06894 | Gentaur Antibodies

Overview: Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880) , makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]) . The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD (+) cofactor.

Category Type: Polyclonal Antibody

Research Areas: Metabolism, Signal Transduction

Synonyms: DHSO, L iditol 2 dehydrogenase, L-iditol 2-dehydrogenase, OTTHUMP00000161939, SDH, Sorbitol dehydrogenase 1, Sorbitol dehydrogenase, SORD 1, SORD, SORD1

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC021085

Clonality: Polyclonal

Immunogen: Fusion protein of human SORD

Clone #:

Conjugation: Unconjugated

Swissprot: Q00796

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 0.78 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:100, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SORD Polyclonal Antibody DataSheet