SPACA1 Polyclonal Antibody | G-AB-04622

SPACA1 Polyclonal Antibody | G-AB-04622 | Gentaur Antibodies

Overview: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively.

Category Type: Polyclonal Antibody

Research Areas: Cell Biology

Synonyms: SACA1, SAMP32, SPACA1, Sperm acrosomal membrane-associated protein 32, Sperm acrosome membrane-associated protein 1

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC029488

Clonality: Polyclonal

Immunogen: Fusion protein of human SPACA1

Clone #:

Conjugation: Unconjugated

Swissprot: Q9HBV2

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 0.84 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:100, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SPACA1 Polyclonal Antibody DataSheet