SPAST Polyclonal Antibody | G-AB-12376
- 3 to 5 Working Days
- Human, Mouse
SPAST Polyclonal Antibody | G-AB-12376 | Gentaur Antibodies
Overview: This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The encoded ATPase may be involved in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequences have not been determined. Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Metabolism, Signal Transduction
Synonyms: SPAST, ADPSP, FSP2, SPG4, spastin
Reactivity: Human, Mouse
Gene ID: 6683
Immunogen: Recombinant fusion protein of human SPAST (NP_055761.2) .
Calculated MW: 54 kDa/58 kDa/63 kDa/67 kDa
Observed MW: 52 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.