SQSTM1 / p62 Polyclonal Antibody | G-AB-11852
- 3 to 5 Working Days
- Human, Mouse, Rat
SQSTM1 / p62 Polyclonal Antibody | G-AB-11852 | Gentaur Antibodies
Overview: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction
Synonyms: SQSTM1, A170, DMRV, FTDALS3, NADGP, OSIL, PDB3, ZIP3, p60, p62, p62B
Reactivity: Human, Mouse, Rat
Gene ID: 8878
Immunogen: Recombinant fusion protein of human SQSTM1 / p62 (NP_001135770.1) .
Calculated MW: 38 kDa/47 kDa
Observed MW: 62 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IHC, IF
Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.