SSX2 Polyclonal Antibody | G-AB-11424

SSX2 Polyclonal Antibody | G-AB-11424 | Gentaur Antibodies

Overview: The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX1 and SSX4 family members, have been involved in t (X;18) (p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate, GeneID: 727837, located about 45 kb downstream in the opposite orientation on chromosome X.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling

Synonyms: SSX2, CT5.2, CT5.2A, HD21, HOM-MEL-40, SSX

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 6757

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human SSX2 (NP_783629.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q16385

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SSX2 Polyclonal Antibody DataSheet