STAT2 Polyclonal Antibody | G-AB-03047

STAT2 Polyclonal Antibody | G-AB-03047 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN) , this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G) , in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms: Homo sapiens interferon alpha induced transcriptional activator, interferon alpha induced transcriptional activator, ISGF 3, ISGF3, MGC59816, P113, signal transducer and activator of transcription 2 113kD, Signal transducer and activator of transcription 2, STAT113, Stat2, STAT2

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_005410

Clonality: Polyclonal

Immunogen: Synthetic peptide of human STAT2

Clone #:

Conjugation: Unconjugated

Swissprot: P52630

Santa Cruz: sc-950/sc-839/sc-476/sc-22816

Calculated MW: 98 kDa

Observed MW:

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

STAT2 Polyclonal Antibody DataSheet