STAT4 Polyclonal Antibody | G-AB-11426

STAT4 Polyclonal Antibody | G-AB-11426 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms: STAT4, SLEB11

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 6775

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human STAT4 (NP_003142.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q14765

Santa Cruz:

Calculated MW: 85 kDa

Observed MW: 76 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC, IF

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

STAT4 Polyclonal Antibody DataSheet