TANK Polyclonal Antibody | G-AB-11310
- 3 to 5 Working Days
- Human, Mouse, Rat
TANK Polyclonal Antibody | G-AB-11310 | Gentaur Antibodies
Overview: The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Immunology, Signal Transduction
Synonyms: TANK, I-TRAF, ITRAF, TRAF2
Reactivity: Human, Mouse, Rat
Gene ID: 10010
Immunogen: Recombinant fusion protein of human TANK (NP_597841.1) .
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: IF 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.