TAP2 Polyclonal Antibody | G-AB-09313

TAP2 Polyclonal Antibody | G-AB-09313 | Gentaur Antibodies

Overview: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: TAP2, ABC18, ABCB3, APT2, D6S217E, PSF-2, PSF2, RING11

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 6891

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human TAP2 (NP_000535.3) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q03519

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

TAP2 Polyclonal Antibody DataSheet